【作者】 陈晓明； 罗鹏飞；

【Author】 Chen Xiao-Ming Luo Peng-Fei Department of interventional radiology, Guangdong Provincial People’ s Hospital, Guangzhou 510080, China

【机构】 广东省人民医院肿瘤中心介入治疗科；

【摘要】 本文的目的事探讨子宫肌瘤行经导管子宫肌瘤子宫动脉栓塞治疗后的病理变化及临床意义。研究证实, TUAE后肌瘤组织随时间改变呈现动态病理变化,即先发生充血、水肿,随后发生坏死,最后出现纤维组织增生,这一动态病理变化是TUAE后肌瘤体积不断缩小的病理基础。肌瘤坏死的性质包括凝固性坏死和玻璃样坏死,绝大多数呈不完全坏死,因此肌瘤复发是可能的。影响坏死范围的因素包括肌瘤大小与部位及栓塞后时间长短。TUAE后正常子宫组织可能出现炎症反应,但无坏死改变。周围附件器官末梢血管发现栓塞剂,提示TUAE对卵巢、输卵管功能有潜在的影响。更多还原

【Abstract】 It is very important to investigate pathological changes of transcatheter uterine artery embolization (TUAE) for the treatment of uterine fibroids. It has been proves that a regular pathological change with elapse of duration after TUAE occurred in fibroid tissues. Inflammation occurred in fibroid tissues first, then necrosis appeared and finally proliferation of fibrous tissue formed. These dynamic changes of pathology are pathological basis of fibroid volume reduction. Necrosis of fibroid included coagulation necrosis and hyaline-type necrosis which most of them were incomplete. Therefore it is possible for tumor to recur. The factors affecting fibroid necrosis included tumor size, position and elapse of duration after TUAE. Inflammation was found in normal uterine tissue but no necrosis occurred. Embolic agent was found in peripheral vessel of adnexa which may result in damage of function of ovary and fallopian tube.更多还原