【作者】 李笑梅； 韩建英； 徐致祥； 连士勇； 邢海平； 谭家驹； 刘志才； 王民宪； 孔芳君； 张栓虎； 司建华； 田普琴；

【Author】 Han Jian-Ying Lian Shi-Yong Xu Zhi-Xiang et al An-yang Sanitation and Anti-epidemic Station Anyang Henan , 455000 China

【机构】 河南省安阳市疾病预防控制中心； 广东省佛山市第一人民医院； 河南省林州市肿瘤防办；

【摘要】 目的:探讨改水对林州市食管癌发病率、死亡率的影响。方法:对10个乡344个村,2001-2003年与1996-1998 年两次结果进行队列研究,将调查村按照改水类型分为实验改水村[①深机井、井深≥100米、集中供水②污染指数小于 1．5③改水≥6年]、非实验改水村[未能完全达到上述三条标准者深机井(井深<100米)集中供水改水<6年;或不包括山泉水的非机井水]、未改水村(只饮用分散式山泉水)。结果:两次调查横断面结果一致,实验改水村发病率、死亡率最低,未改水村最高;队列研究结果表明:01-03年实验改水与 96—98年未改水组比较,食管癌发病率、死亡率分别下降 41．9％、34．8％,x2=18．79,P<0．01,x2=9．07,P<0．01, 有显著的统计学意义;96—98年第一个改水5年为非实验改水,6年后(2004年)达到实验改水,发病率、死亡率分别下降了34％,36％,x2=16．44,P<O．01; x2=17．34,P<0．01, 有显著的统计学意义。结论:实验改水著性降低林州市食管癌发病率和死亡率。更多还原

【Abstract】 Objeotive: To observe the prospective influence of different kinds of water on morbidity and mor- tality of esophageal cancer (EC) in Linzhou residents. In order to test the hypothesis of "nitrogenous compound metabolised cycling" in etiology of EC. Methods: Based on the investigating data collected in 96-98 and 01-03 among which data were from Linzhou Institute of Prevention and Treatment of EC. Three kinds of water were included. standardized deep well Water(SDWW) from the well with the depth exceeding 100 meters ,finished time exceeding 6 years , unstandardized deep well Water (UDWW) and mountainous spring water(MSW).The morbidity and mortality of (EC) in the related population. Results: There were 281458 residents, 165 villages to drink SDWW, 183289 residents, 129 villages to drink UDWW ,18119 people, 14 villages to drink MSW. The morbidity and mortality of EC is lower (01-03) in residents drinking of the SDWW than those of residents drinking of the MSW (96-98). It were significantly reduced 41.9%, 34. 8% respectively ( X2=18.79, P<0.01, X2=9.07, P<0.01 ). It were no statistical significantly reduced in people drinking of the MSW. Conclusion: Aftre water supply changed ,the drinking water quality turned better ,the morbidity and mortality of EC in Linzhou residents have showed a decreasing trend.更多还原