【作者】 陈晓明； 庄文行； 罗鹏飞； 杜娟； 左约维； 胡小平； 洪淡华；

【Author】 CHEN Xiaoming DU Juan ZUO Yuewei Department of Oncology,Guangdong Provincial People’s Hospital,Guangzhou 510080,P.R.China

【机构】 广东省人民医院肿瘤科； 广东省人民医院妇产科；

【摘要】 目的:探讨经导管子宫动脉栓塞(TUAE)治疗子宫腺肌病的效果。方法:25 例子宫腺肌病患者接受 TUAE 治疗,25例均伴有继发性痛经,其中21例伴月经增多,10 例伴轻到中度贫血。25例中弥漫型腺肌病10例,局灶型腺肌病15例,其中4例尚合并子宫肌瘤。所有病例均采用经导管两侧子宫动脉注射超液态碘油平阳霉素乳剂(LPE)加明胶海绵颗粒栓塞,其中碘油用量6-10ml(平均8ml),平阳霉素用量8mg,明胶海绵0．5～1．5 块(6cm×3cm×0．3cm/块)。结果:所有病例随访超过半年,痛经缓解有效率达96．0%(其中痛经消失占80．0%),月经改善有效率达100%(其中月经恢复正常占76．2%)。12例贫血患者栓塞后3-6个月血红蛋白浓度均得到显著升度或恢复正常;栓塞后6个月 B 超复查子宫体积平均缩小44．1%,21个局限性病灶体积平均缩小58．2%。所有病例无严重并发症发生。结论:TUAE 治疗子宫腺肌病具有较好的近期疗效,远期效果有待进一步观察。更多还原

【Abstract】 OBJECTIVE:TO invertigate the efficiency of transcatheter uterine artery embolization (TUAE) for adenomyosis.METHODS:Twenty-five women with adenomyosis underwent TUAE.The patients were affected by secondary menstrual pain(100%) associated with menorrhagia in 21 cases and anaemia in 10 cases.Of the 25 patients,10 had diffuse adenomyosis,15 had focal adenomyosis.Four of 25 patiens was still associated with uterine fibroids.In all patients,bilateral uterine artheries were embolized by injecting lipiodol-pingyangmycin emulsion(LPE) and gelfoam sponge (GS) partcles.The amount of lipiodol was 6ml to 10ml (mean,8ml) every patient.The dose of pingyangmycin was 8mg.The amount of GS ranged form half piece to one piece and half (6cm×3cm×0.3cm/piece). RESULTS:The improvement of menstrual pain occurred in 96.0%(disappeared in 80%).The resolution of menorrhagia occurred in 100% (normal in 76.2%).It was observed that the blood level of hemoglobin had been increased significantly or had recoveried to normal 3-6 months after TUAE in 12 women with anaemia.Ultrasonic tomography showed that the average decrease of uterine volume and 21 focuses at 6 months after TUAE was.44.1% and 58.2% respectively.No serious complications happened.CONCLUSION:TUAE shows a preliminary good result for adenomyosis,but its long-trem effectiveness is still need to observe.更多还原