【作者】 鲍芳； 韩三阳； 沈红霞； 姚建林； 顾仁敖；

【Author】 BAO Fang HAN San-yang SHEN Hong-xia YAO Jian-lin GU Ren-ao Department of Chemistry,Suzhou University,Suzhou 215006,China

【机构】 苏州大学化学系；

【摘要】 在Fe-Oxide纳米粒子表面还原金制备不同壳层厚度的Fe-Oxide/Au磁性核壳纳米粒子,并用SEM表征其形貌。结果表明,Fe-Oxide聚集体已被金包裹并且核壳粒子表面呈现出类似毛刺状的结构。用Py作为探针分子的SERS对Fe-Oxide/Au磁性纳米粒子施加磁场后的靶向效果进行检测,发现SERS强度随着磁场施加时间与金壳层厚度的增加而增强。并且这种核壳纳米粒子能检测到低浓度的Py溶液.将作为一种很好的基底用来进行生物分子的分离与检测。更多还原

【Abstract】 Fe oxide core/Au shell nanoparticles were prepared by the reduction of Au³⁺onto the surfaces of Fe oxide nanoparti- des and characterized by scanning electron microscopy（SEM）.The results revealed that the prepared core/shell nanoparticles were covered by Au shell and the surfaces of the core/shell particles were jagged after the initial addition of Au³⁺.Surface en- hanced Raman scattering（SERS）activities of these magnetic nanoparticles were studied by using pyridine（Py）as a probe mole- cule after a magnet was used to concentrate the colloid.It was found that the SERS intensity depended on the Au shell thickness of the core/shell nanoparticles and-strengthened with the increasing shell thickness.The detection limit for Py can be very low by using the magnetic Fe oxide core/Au shell nanoparticles and even down to 10^-7mol·L^-1.更多还原