【作者】 张静； 王艳霞； 杨新林；

【Author】 Jing Zhang, Yanxia Wang, Xinlin Yang* School of Life Science and Technology,Beijing Institute of Technology, Beijing 100081

【机构】 北京理工大学生命科学与技术学院；

【摘要】 <正>通过1,3-偶极环加成反应合成中间体N-取代的3,4-富勒烯吡咯烷,利用α-氨基与α-羧基均被保护的天冬氨酸或谷氨酸的非α-羧基与中间体N-取代的3,4-富勒烯吡咯烷衍生物的活化羟基进行缩合反应,产物脱保护后得到了新型α-富勒烯氨基酸:富勒烯天冬氨酸和富勒烯谷氨酸。采用更多还原

【Abstract】 Aspartic acid and glutamic acid with protected α-amino and α-carboxyl groups had been used to react with the activated hydroxyl group of N-substituted 3,4-fullero pyrrolidine. The products were deprotected, affording two monofullerene α-amino acids, monofullerene aspartic acid (mFas) and monofullerene glutamic acid (mFgu). Then a bifullerene glutamic acid conjugate (bFguC) was synthesized by reaction of mFgu containing protected amino group with N-substituted 3, 4-fullero pyrrolidine.更多还原