【作者】 欧阳健明； 袁欢欣；

【Author】 Ouyang Jian-Ming Yuan Huan-Xin (Institute of Biomineralization and Lithiasis Research , Jinan University, Guangzhou 510632)

【机构】 暨南大学生物矿化与结石病防治研究所,化学系；

【摘要】 比较研究了乙二醇二乙醚二胺四乙酸钾(K2EGTA)、氨基三乙酸钾(K2MTA)、二乙三胺五乙酸钾(K2DTPA)、乙二胺四乙酸钾(K2EDTA)和环已二胺四乙酸钾(K2CDTA)对草酸钙(CaOxa)结晶的影响。从氨羧盐的羧基相对含量、分子结构和羧基的空间位置、与钙离子的配位能力及其配位方式等角度讨论了其抑制COM晶体成核、生长、聚集及诱导COD形成的化学基础。更多还原

【Abstract】 The studied aminocarboxylates included dipotassium glycoletherdiamino- tetraacetate(K2EGTA), dipotassium aminotriacetate (K2NTA), dipotassium diethylenetriamine- penteacetate (K2DTPA), dipotassium ethylene diamine tetraacetate (K2EDTA) and dipotassium cyclohexanediamine tetraacetate (K2CDTA). K2EDTA and K2CDTA could decrease the specific surface area of COM aggregates and change the morphology of COD, K2NTA and K2DTPA could inhibit the aggregation of COM greatly and induce the formation of COD with small size, whereas K2EGTA had no significant effects on CaOxa growth. This result was discussed in terms of the relative content of carboxylic groups, chemical structure, the chelation mode with Ca2+ ion and the coordination mode of aminocarboxylates. It demonstrated K2NTA and K2DTPA might be beneficial to the prevention and cure of urinary stones.更多还原