【作者】 吴婧； 郁露； 孙素琴；

【Author】 WU Jing, YU Lu, SUN Su-qin Department of Chemistry, Tsinghua University, Beijing 100084, China

【机构】 清华大学化学系；

【摘要】 采用红外光谱法研究丹参配方颗粒制备过程质量控制,并对不同制药公司丹参配方颗粒进行分析。 1 160~1 000 cm-1用于判断所添加辅料类型及含量,1 608 cm-1附近特征吸收峰用来评价配方颗粒中有效成分相对含量。红外光谱法可用于丹参配方颗粒的质量控制和制备工艺的判断。更多还原

【Abstract】 Fourier transform infrared (FTIR) spectroscopy has been applied to the research on the quality control of Danshen formula particles manufacturing process and to the analysis of formula particles from different pharmaceutical factories. The authors can confirm the sort and relative content of supplementary materials by the characteristic absorption peaks between 1 160 and 1 000 cm-1 , and evaluate the relative content of effective component by the characteristic absorption peaks at 1 608 cm-1. FTIR spectroscopy is an effective and fast method for not only the quality control of Danshen formula particles but also the identification of manufacturing techniques.更多还原