节点文献
抑制HL-60的哌嗪衍生物的合成和生物评价
Synthesis and Biological Evaluation of Piperazine Derivatives for HL-60 Human Leukemia Cells
【作者】 师自法; 杨东; 刘增路; 曹小平; 崔景荣; 冉福香;
【Author】 Zi-Fa Shi,a Dong Yang,a Zeng-Lu Liu,*a,b Xiao-Ping Cao,*a Fu-Xiang Ran,c Jing-Rong Cui,*c aState Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, 730000, Lanzhou; bSchool of Pharmacy, Shanghai Jiao Tong University, 200240, Shanghai and cThe State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmacy Sciences, Peking University, 100083, Beijing
【机构】 兰州大学化学化工学院功能有机分子国家重点实验室; 北京大学药学院天然药物及仿生药物国家重点实验室;
【Abstract】 A series of piperzine derivatives with long chain which is connector of two conjugated systems have been synthesized. These compounds have been evaluated for HL-60 Human Leukemia Cells, which display significant affinity (IC50 = ~10-6 M).
- 【会议录名称】 中国化学会第二十五届学术年会论文摘要集(下册)
- 【会议名称】中国化学会第二十五届学术年会
- 【会议时间】2006-07
- 【会议地点】中国吉林长春
- 【分类号】TQ460.1
- 【主办单位】中国化学会