【作者】 于晓强； 艾希成； 封继康； 蒋民华；

【Author】 Xiao-Qiang1 Yu, Xi-Cheng Ai2, Feng-Ji Kang3, Hai-Lun4, Min-Hua Jiang1 1State key lab. of Crystal Materials, Shandong University, 250100 Jinan 2State key lab. for Structural Chemistry of Unstable and Stable Species, Institute of Chemistry, CAS, 100080 Beijing 3 State Key Lab. of Theoretical and Computational Chemistry, Institute of Theoretical Chemistry,The College ofChemistry, Jilin University, Changchun 130023

【机构】 山东大学晶体材料国家重点实验室； 中国科学院化学研究所分子动态与稳态结构国家重点实验室； 吉林大学理论化学计算国家重点实验室；

【Abstract】 We have synthesized and characterized two water-soluble fluorescence molecules, 3-(1-methyl-4-viniyllpyridinium)-9-ethylcarbazole iodide (MVEC) and 3,6-bis(1-methyl-4-viniyllpyridinium)-9-ethylcarbazole diiodide (BMVEC). And, the absorption and fluorescence spectra of both molecules have clear response for interacting with ctDNA. From these spectral responses we notice that BMEVC has more complicate interactions with ctDNA than that of MVEC. Additionally the significant two-photon fluorescence amplified response induced by ctDNA has suggested a potential material for DNA labeling.更多还原