【作者】 王军波； 吴旻宪； 崔铮； 崔占峰；

【Author】 WANG Jun-bo~1 WU Min-xian~2 CUI Zheng~2 CUI Zhan-feng~3 (1.State Key Lab.of Transducer Technology,Institute of Electronics,Beijing 100080,China; 2.Central Microsture Facility,Ruthur ford Appleton Laboratory,Oxford OX11OQX,UK; 3.Department of Engineering Sciences,University of Oxford,Oxford OX13PJ,UN)

【机构】 中国科学院电子学研究所传感技术国家重点实验室； 英国卢瑟福国家实验室； 英国牛津大学工程系；

【摘要】 以生物微反应器中培养液 pH 在线监测为目标,研制出一种基于光度吸收原理的阵列光纤传感器。利用 MEMS 加工工艺,制备出传感器的阵列吸光池芯片,采用光学软件对吸光池进行优化设计,提高了传感器光传输效率,并通过 CFD 软件进行流体模拟,优化吸光池结构,降低了溶液死体积,缩短传感器响应时间。实验结果表明,所研究的传感器阵列检测灵敏度为0．83 V/pH,响应速度快,可用于多个生物微反应器的 pH 在线监测。更多还原

【Abstract】 A novel optical fibre sensor array based on Lambert-Beer law was developed for online monitoring of pH in microbioreactor.It was fabricated through MEMS processing.Different thicknesses of detection pole were tested by optical simulation to acquire high light transmission efficiency.Two kinds of detection pole structures were analyzed by CFD simulation to minimize the dead zone and shorten response time of the sensor.Experiments show that the sensitivity of the optical fibre sensor array is 0.83 V/pH and it can be used for on-line monitoring of pH in multi-microbioreactor with shorter response time.更多还原