【作者】 李胜联； 施文祥； 欧超燕； 郑雅丹； 罗华； 瞿新贞； 郭彩霞；

【Author】 Li Sheng lian~1 Shi Wen Xiang~1 Ou Chao yan~1 Zheng Ya Dan~2 Luo Hua~2 Ou Xin Zhen~2 Guo Cai Xia~2 1 Department of preventive medicine,Gui]in Medical college,2 Grade 2002 of C]inical Medicine Department Guilin Medical College

【机构】 桂林医学院预防医学教研室； 桂林医学院；

【摘要】 目的建立多个变异系数显著性检验的计算与分析方法。方法采用Bonferroni法确定变异系数显著性检验的水准及各实验组分别与同一对照组比较的变异系数显著性检验计算分析方法。结果确定的显著性检验水准为α~1=0.0167。与对照组比较,30mg/kg及60mg/kg组血清ALT活性的均数显著性检验均无统计学意义(P>0.0167),而变异系数的显著性检验均有统计学意义(P<0.0167);60mg/kg组血清AST活性均数显著性检验未见有统计学意义(P>0.0167),而变异系数的显著性检验有统计学意义(P<0.0167)。结论同时使用均数的显著性检验与变异的显著性检验,才能全面反应检测指标的变化情况。更多还原

【Abstract】 AIM:The purpose of this study was to establish the methods of calculating and the analysis multi-Coefficient of variation significance test for the toxicology study. Methods:To confirm significance level with Bonferroni and then carry out the significance test of multi-coefficient of variation.Results:The significance level of multi-Coefficient of variation significance test was confirmed asα′=0.0167. Comparing to control group,the activity of ALT in serum both in 30mg/kg and 60mg/kg groups did not changed in the average significance test,while changed in the variation significance test.The activity of AST in serum in 60mg/kg groups did not change in the average significance test,while changed in the variation significance test.Conclusion:The using of the average significance test and the variation significance test simultaneity will show the changes of the indexes completely.更多还原