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桑宁茶多糖对糖尿病小鼠的降血糖作用研究
Hypoglycemic Effect of Polysaccharide in Mulberry Tea on Normal and Diabetic Mice
【作者】 廖森泰; 邹宇晓; 郑祥明; 陈卫东; 刘学铭; 徐玉娟; 张友胜;
【Author】 LIAO Sentai ZOU Yuxiao ZHENG Xiangming CHEN Weidong LIU Xueming XU Yujuan ZHANG Yousheng (Sericultural Research Institute of Guangdong Academy of Agricultural Science,Key lab of Guangdong for Deep Processing of Fruit & Vegetable,Guang zhou 510610)
【机构】 广东省农业科学院蚕业研究所广东省果蔬深加工重点实验室;
【摘要】 为探寻桑宁茶多糖对糖尿病模型小鼠的降血糖作用,利用分级纯化的方法,得到3种不同纯度的桑宁茶多糖(Ⅰ、Ⅱ、Ⅲ);以常规降糖药格列本脲(优降糖)为阳性治疗对照,通过对糖尿病小鼠进行降血糖治疗试验,研究了3种桑宁茶多糖的降血糖作用。结果表明,3种桑宁茶多糖对链脲佐菌素诱导的糖尿病小鼠均有显著的降血糖作用,降糖效果以初步纯化的多糖效果最好,且效果均优于格列苯脲。
【Abstract】 To study the hypoglycemic effect of polysaccharide in Mulberry Tea,threekinds of polysaccharides were separated and purified from the Mulberry Tea,and thestreptozotocin-induced diabetic mice were treated with these three kinds ofpolysaccharides respectively,the anti-diabetic activity of the standard drug,glibenclamide was choosed as electropositive control.The results from pre-andpost-treatment analysis of blood glucose showed that three kinds of polysaccharidescould decreased the concentration of blood glucose significantly,and among the threekinds of polysaccharides the therapy effect of polysaccharideⅡis most remarkable,furthermore their therapy effect were more remarkable than glibenclamide.
- 【会议录名称】 中国蚕学会第四届青年学术研讨会会议论文集
- 【会议名称】中国蚕学会第四届青年学术研讨会
- 【会议时间】2004-11
- 【会议地点】中国广州
- 【分类号】R285
- 【主办单位】中国蚕学会