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亲属活体肾移植的药学监护和治疗窗浓度的探讨

The pharmaceutical care of the living-related danor kidney transplantion

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【作者】 张宁范青吕慧怡

【Author】 Zhang Ning,Fan Qing(Dept.of Pharmacy,the Second Affiliated hospital of Dalian Medical University,Dalian 116027)

【机构】 大连医科大学附属二院药剂科

【摘要】 【目的】确保亲属活体肾移植术后供、受体用药均安全、有效、经济。【方法】通过治疗药物监测,建立药历,进行疗效评价和做好咨询等对肾移植患者实施药学监护。【结果】在小样本范围内确定了0~1个月、1~3个月CsA的治疗窗浓度。【结论】通过药学监护,提高了肾移植患者术后的用药安全性,改善了患者的生存质量。

【Abstract】 OBJECTIVE:To ensure the post-operation dosage schedule of the donor and recipient in the living-related danor kidney transplantion(LDKT)is safe,effective and economic.METHODS:To practice the pharmaceutical care of the patients by the way of TDM,establishment of medical history,evaluation of therapeutic effect and do a good job of consultationcon.RESULT:The therapeutic window scope of the CsA was established during the one month to three month in small sample,and the therapeutic windows clinical meaning has been discussed in brief.CONCLUSION:By the way of pharmaceutical care,the safety for the drug which was administrated to kidney transplantation’s patient.The quality of live has been noticeably improved.

【关键词】 肾移植药学监护治疗窗浓度
【Key words】 Kidney transplantationpharmaceutical careTDM
  • 【会议录名称】 2008年中国药学会学术年会暨第八届中国药师周论文集
  • 【会议名称】2008年中国药学会学术年会暨第八届中国药师周
  • 【会议时间】2008-10
  • 【会议地点】中国河北石家庄
  • 【分类号】R699.2;R95
  • 【主办单位】中国药学会、河北省人民政府
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