【作者】 霍长虹； 张嫚丽； 李作平； 史清文；

【Author】 Chang-Hong Huo, Men-Li Zhang, Zuo-ping Li, Qing-Wen Shi Department of Natural Product Chemistry, School of Pharmaceutical Sciences, Hebei Medicinal University, 361 Zhongshan East Road, 050017, Shijiazhuang, Hebei Province, P. R. China

【机构】 河北医科大学药学院；

【摘要】 目的研究东北红豆杉(Taxus cuspidata)针叶中紫杉烷类化学成分。方法用色谱法分离,用理化性质及波谱方法鉴定结构。结果从东北红豆杉中分离得到 6 个化合物, 分别鉴定为 10 β—hydroxy-2α,9α,13α—triacetoxy-5α—cinnamatetaxa-4(20),11-diene(I), 7,13-dideacetyl-9,10-debenzoyl taxchinin C (II), 2-deacetyltaxin B (III), 7,9-dideacetyl- 5-decinnamoyltaxinine J (IV), 2α,13α-dihydroxy-9α,10 β-diacetoxy-5α-cinnamatetaxa-4(20),11-diene(V),5-decinnamoyltaxuspine D(VI)。结论化合物I,II,III,V和VI均为首次从该植物中获得。更多还原

【Abstract】 OBJECTIVE To study the taxoids in the needles of Taxus cuspidata. METHODS Chromatographic methods were used to isolate compounds from the needles of T. cuspidata, and chemical and spectral methods were used to elucidate the structures of the isolated compounds. RESULTS Six taxane diterpenoids were isolated from the needles of T. cuspidata and identified as 10β-hydroxy-2α,9α,13α-triacetoxy-5α-cinnamate- taxa-4(20),11-diene (I), 7β,13α-dideacetyl-9,10-debenzoyltaxchinin C (II), 2-deacetyltaxin B (III), 7β,9α-dideacetyl-5-decinnamoyltaxinine J (IV), 2α,13α-dihydroxy-9α,10β-diacetoxy-5α-cinnamatetaxa-4(20),11-diene (V), 5-decinnamoyltaxuspine D (VI). CONCLUSION Compounds I, II, III, V and VI were obtained from this plant for the first time.更多还原