【作者】 任乃林； 李红；

【Author】 Ren Nailin Li Hong Department of Chemistry,Hanshan Normal university,Chaozhou 521041,China

【机构】 韩山师范学院化学系；

【摘要】 在1%硝酸介质中,诺氟沙星（NFLX）与 Fe（Ⅲ）在室温下形成稳定的橙黄色配合物,其最大吸收波长为 430nm,摩尔吸光系数为ε=2.36×10³ L.mol^-1·cm^-1,线性范围为5μg/mL-120μg/mL。本法的相对标准偏差为2. 0%（n=10）。应用拟定的方法对含诺氟沙星药物的胶囊进行了含量测定,结果满意。更多还原

【Abstract】 A method for the determination of norfioxacin in the capsules by spectrophotometry has been developed.It is found that in 1% HNO₃ medium,Fe（Ⅲ）reacts with norfloxacin to form yellow-orange colored complex with a maximum absorption at 430nm.The apparent molar absorptivity is ε=2.36×10³ ·(L.mol^-1·cm^-1),Beer’s law is obeyed in the concentration range of 5μg/mL-120μg/mL for norfloxacin.The method was used for direct determination of norfloxacin in the norfloxacin capsules,and got satisfactory results.更多还原