【作者】 李勤； 陈宁； 崔育新；

【Author】 QinLi NingChen YuXinCui* (National Laboratory of Natural and Biomimetic Drugs,Medical and Healthy Analysis Center,Peking University,Beijing,100083)

【机构】 北京大学天然药物及仿生药物国家重点实验室医药卫生分析中心；

【摘要】 <正>人参（Panax ginseng C．A．Mey）属五加科药用植物,其根、茎、叶、花、果均供药用,具有丰富多彩的生物学活性。人参皂苷（ginsenoside）已经被公认为人参的“有效组合分子群”之一,包括人参皂苷 Rg₁,Rg₃,Rb₁,Re。这些皂苷或是原形发挥作用,或是代谢产物发挥作用。而且,在人参炮制过程中,某些人参皂苷的结构亦发生变化。在这些研究中人参皂苷的结构鉴定就显得非常重要了。更多还原

【Abstract】 Panax ginseng is a kind of famous Chinese traditional drug,it has exceptional biological activity.Triterpenoid saponins is its majoy ingredient.Triterpenoid saponins is divided into two parts,one is 20（s）-protopanaxadiol,the other is 20（s）-protopanaxatriol.The structural diversity of gingseng lies mainly in their sugar moieties.We have already heard so many reports about the triterpenoside saponins’s ¹³CNMR,but we almost haven’t heard the report about it’s¹HNMR.This paper report the complete ¹HNMR shift assignments of ginsenoside Rg₁,Rg₃,Rb₁,Re.The assignments were corroborated by careful analysis of ¹H-¹H COSY,HSQC and HMBC spectra..These results will contribute to the revealing of the relationship between the conformational analysis and biological activity of this series of ginseng.更多还原