【作者】 任杰； 洪海燕；

【Author】 Ren Jie Hong Haiyan (Institute of Nano and Bio-Polymeric Materials,School of Material Science and Engineering,Tongji University,200092,Shanghai,China)

【机构】 同济大学,材料科学与工程学院,纳米与生物高分子材料研究所；

【摘要】 采用本体聚合法制得了一系列聚乳酸-聚乙二醇(PLA-PEG)嵌段共聚物,用硅烷偶联剂等对四氧化三铁进行改性, 并采用相分离法以 PLA-PEG 为基材制得了具有一定磁响应性的改性四氧化三铁复合微球。用核磁共振(~1H-NMR)、红外光谱分析了共聚物的结构和组成,用 GPC 测得了聚合物的分子量,研究了丙交酯／PEG 投料比、PEG 分子量对聚合产物结构、分子量的影响。研究了不同改性剂改性的四氧化三铁复合微球的粒径、磁粉含量、磁响应性等。更多还原

【Abstract】 A series of biodegradable block copolymers of poly-_D,L-lactide-co-polyethylene glycol（PLA-PEG）s were prepared out by ring-opening polymerization of _D,L-lactide with stannous caprylate （Sn（Oct）₂） as catalyst,the magnetic Fe₃O₄ particles were modified by coupling agent,then the PLA-PEG copolymers and magnetic Fe₃O₄ were made into composite particles by phase separation method.The average molecular weight and structure of PLA-PEG were detected by GPC,¹H-NMR and IR.The effects of LA/PEG feed ratio,the molecular weight of PEG on the structure and molecular weight of copolymers were investigated.The sizes,Fe contents,magnetic properties of the composite particles prepared by different modified Fe₃O₄ were also researched.更多还原