【作者】 白东清； 郭永军； 陈成勋； 朱国霞； 闫姗姗； 崔培； 李瑞；

【Author】 BAI Dong-qing GUO Yong-jun CHEN Cheng-xun ZHU Guo-xia YAN Shan-shan CUI Pei LI Rui (Tianjin Key Lab of Aqua-Ecology and Aquaculture,Department of Fishery Science, Tianjin Agricultural College,Tianjin 300384)

【机构】 天津农学院水产科学系天津市水产生态及养殖重点实验室；

【摘要】 本试验进行了迟钝爱德华氏菌对12种抗生素(氯霉素,红霉素,硫酸庆大霉素,氨苄青霉素,羧苄青霉素,盐酸四环素,盐酸万古霉素,头孢噻肟钠,利福平,卡那霉素硫酸盐,链霉素,Penicillin G)及8种联合药物的敏感性研究。采用试管二倍稀释法测定抗生素对迟钝爱德华氏菌的最小抑菌浓度(MIC)、最小杀菌浓度(MBC)。结果表明:硫酸庆大霉素、卡那霉素硫酸盐、盐酸四环素的抑菌效果最好,其最小抑菌浓度(MIC)分别为0.05μg/ml、0.8μg/ml、1.6μg/ml,最小杀菌浓度(MBC)分别为0.05μg/ml、3.2μg/ml、100μg/m;联合药物中硫酸庆大霉素+羧苄青霉素、硫酸庆大霉素+盐酸四环素、氨苄青霉素+链霉素的抑菌效果最好,其最小抑菌浓度和最小杀菌浓度均为0.05μg/ml。更多还原

【Abstract】 The sensitivity of Edwardsiella tarda against 12 kinds of antibiotics(Chloromycetin, Erythromycin,Gentamicin sulfate,Ampicillin,Carboxymethyl benzylpenicillin,Tetracycline hydrochloride, Vancomycin,Cefotaxime sodium,Rifampicin,Kanamycin sulfate,Streptomycin,Penicillin G)and 8 kinds of compound antibiotics were investigated in this study.The filtered antibiotics’ minimum inhibitory concentration and minimum bactericidal concentration against Edwardsiella tarda were researched through the tube dilution double method.The result showed that the inhibitory facilities of Gentamicin sulfate, Kanamycin sulfate and Tetracycline hydrochloride were highest.The minimum inhibitory concentrations of Gentamicin sulfate,Kanamycin sulfate and Tetracycline hydrochloride were 0.05μg/ml,0.8μg/ml and 1.6μg/ml,respectively,while their minimum bactericidal concentrations were 0.05μg/ml,3.2μg/ml and 100μg/ml,respectively.In compound antibiotics experiment,the inhibitory facilities of Gentamicin Sulfate plus Carboxymethyl benzylpenicillin,Ampicillin plus Tetracycline hydrochloride and Ampicillin plus Streptomycin were highest.Their minimum inhibitory concentrations and minimum bactericidal concentrations both were 0.05μg/ml.更多还原