【作者】 王斌； 徐少勇； 常青； 胡素芳； 叶克凤；

【Author】 WANG Bin, XU Shao -yong, CHANG Qing, HU Su -fang, YE Ke -feng(Department of Gastroenterology, the Affiliated People’s Hospital of Shiyan, Yunyang Medical College, Shiyan, Hubei 442000, P. R. China)

【机构】 湖北郧阳医学院附属人民医院消化科；

【摘要】 目的探讨IHb测定对Hp的诊断价值。方法180例慢性胃炎患者胃镜检查时,测定胃IHb与Hp检测,对Hp阳性患者80例,行根除治疗后1个月,进行了IHb测定和Hp检测。结果180例患者中,Hp阳性者为102例,阴性者78例,两组间IHb值比较差异有显著性(Jp<0.01)。当把IHb判定Hp阳性分界值设定为60时,对Hp感染诊断的敏感性为89.22%,特异性为93.59%,诊断准确性91.11%。根除Hp治疗1月后,根除成功71例中,根除前、后1个月IHb值分别为(65.2±4.7)、(56.7±4.3),两者比较差异有显著性(P<0.01);根除不成功9例中,根除前、后1个月IHb分别为(64.5±4.6)、(63.6±4.5),两者比较差异无显著性(P>0.05)。结论进行胃镜检查时,可以迅速而简便测定胃IHb值对Hp感染和除菌诊断是有价值的,值得推广应用;但IHb对诊断Hp感染设定值还需进一步研究。更多还原

【Abstract】 [ Objectives ] To evaluate the efficacy of index of haemoglobin (IHb) on diagnosis of Helicobacter pylori (Hp) with chronic gastritis. [Methods] Both IHb and Hp were detected in 180 patients with chronic gastritis when they accepted gastroscope detection. Both IHb and Hp were detected again in 80 Hp positive patients after they accepted eradicated therapy 1 month or so. [ Results ] There were 102 patients whose Hp detection showed positive in 120 patients with chronic gastritis. The value of IHb in the Hp positive patients was significantly different from those of Hp negative patients (P <0.01). If we supposed that value of IHb to diagnose Hp positive was 60, the sensitivity of IHb on diagnosis of Hp was 89. 22% , while the specificity, 93. 59% , and nicety of judgment, 91. 11%. There were 80 patients who accepted eradicated therapy. In 71 patients who had successfully eliminated Hp, the value of IHb before eradicated therapy were (65.2±4.7) while after eradicated therapy was (56. 7±4. 3) , There was significantly difference IHb between before eradicated therapy and after eradicated therapy (P <0. 01). In 9 patients who have not successfully eliminated Hp, the value of IHb before eradicated therapy were (64.5±4.6) while after eradicated therapy was (63.6 ±4.5). There was no significantly difference between the value of IHb of the patients who had successfully eliminated Hp and those who not (P >0. 05). [Conclusions] When patients accepted gastroscope detection, IHb detection is quick and convenient. The value of IHb is meritorious on diagnosis of Hp as well as when Hp is eliminated. But the value of IHb to diagnose Hp is still unclear.更多还原