【作者】 冉令华； 阮晓钢；

【Author】 Ran Linghua Ruan Xiaogang (Electronic Information and Control Engineering SchoolBeijing University of Technology,Beijng 100022)

【机构】 北京工业大学电子信息与控制工程学院；

【摘要】 启动子是DNA序列转录的起始信号。作为基因表达和调控所必需的重要信号,启动子的研究一直受到研究人员的关注。本文运用人工神经网络方法,并结合大肠杆菌基因分子生物学有关理论与统计事实,研究了大肠杆菌启动子中除了两个显著的保守序列外,其它几个非显著序列元件对启动子识别的影响。更多还原

【Abstract】 In this paper, a neural network method was applied to analysis the promoter non-canonical sequence elements in E.coli gene promoter. We selected different sequence length as samples to analyze the influence of different Non-canonical sequence elements. And we also used sliding windows to slide along promoter sequence. As a result, by using neural network method and E.coli gene theory, we found the non-canonical sequence elements have an influence on the promoter recognition.更多还原