【作者】 路明； 任丽君； 阮秀花； 张效本；

【Author】 LU Ming, REN Li-jun, RUAN Xiu-hua, ZHANG Xiao-ben.el al(Kaifeng Institute of Medical Science. Kaifeng 475000 , Henan Province, China 475000)

【机构】 开封市医学科学研究所口腔科；

【摘要】 目的:探讨阿昔洛韦治疗复发性阿弗他溃疡(RAU)的临床疗效。方法:将79例RAU患者随机分为2组,治疗组41例,口服阿昔洛韦(ACV)片200mg/次,每天5五次,连服8周,局部给予碘氧疗法处理;对照组38例,只采用碘氧疗法处理。结果:治疗组总有效率为90.24%,高于对照组42.11%,两组相比差异有显著性(X2=-20.17,P<0.05),治疗组复发率为27.03%,明显低于对照组100%,两者相比差异也具有显著性(X2=23.80,P<0.005)。结论:ACV治疗RAU疗效满意,对RAU的治疗及预防复发有一定临床价值。更多还原

【Abstract】 OBJECTIVE: To evaluate the therapeutic efficacy of acyclovir (ACV) on recurrent aphthae ulceration. METHODS: 79 patients with recurrent aphthae ulceration were divided into two groups, 41 patients in the treatment group and 38 patients in the control group. The treatment group were given ACV 1000mg /d (continuously for 8 weeks) and iodine-oxygen treatment. The control group was given only iodine-oxygen treatment. RESULTS: The effective rate in the ACV group and control group were 90.24% and 42.11% respectively. Significant difference existed between the two groups (P<0.05). The rate of relapse in the treatment group was lower than that in the control group, and there was a significant difference between the two groups (P<0. 005). CONCLUSION: ACV can get fairly higher efficiency in the treatment of recurrent aphthae ulceration.更多还原