【作者】 廖贵清； 黄洪章； 曾融生； 张志光； 郑有华； 杨小平； 陈卓辉；

【Author】 Liao Guiqing Huang Hongzhang Zen Yongshen Zhang Zhiguang Ynag Xiaopin School of stomatolgy,Sun Yat-sen Vniversity of Medieal

【机构】 中山医科大学口腔医学院；

【摘要】 <正>目的:探讨口腔颌面部恶性肿瘤颈淋巴转移的特征和规律,为临床颈淋巴清扫术提供依据。材料和方法:对65例颈淋巴清扫术标本进行病理检查,并与原发灶特征及淋巴结扪诊状况综合分析。结果:口腔颌面部恶性肿瘤颈淋巴转移率46．2％,其中No～N1a病例转移率为36．4%,N1b～N2b 转移率为66．7％;上颌牙龈癌、口咽癌、舌癌、颌骨中央性癌及口底癌颈淋巴转移率较高,而8更多还原

【Abstract】 Objective: To investigate the patterns of cervical lymphnode metastasis from malignant tumor of oral and maxillofacial regions, and their relationship between the clinicopathological feature of primary lesion and the metastasis. Meterials and Methods: Routine lymphode sections and serial sections were performed on neck dissection specimens obtained from 65 patients including oral cancer, oropharngeal cancer and central cancer of jaws. Results: The total rate of cervical lymphnode metastasis was 46.2% (30/65), the rate of occult metastasis in cases without palpable lymphnode was 46.2% (10/26), that with palpable soft lymphnodes was 33.3%(14/21), and that with palpable hard, immovable lymphnodes was 66.7% (14/21). The rate of cervical lymphnode metastasis from oropharyngeal cancer, cancer of uppergingiva, toungue cancer of floor of mouth and central carcinoma of jaws higher than that from the others of oral and maxillofacial regions. The cervical lymphnode metastasis rate of tumor with well differentiation was 27.0% (10/37), that with medium and low differentiation was 71.4% (20/21). There were 7 cases detected metastasis in subclinical lymphnodes by serial section, while found no metastasis in the propagated lymphnodes from the same specimen. Conclusion: The incidence of cervical metastasis was closely related to the location, pathological differentiation of the primary lesion, and especially to the condition of lymphnode. Serial section was necessary for every specimen to accurately detect the occult lymphnode metastasis.更多还原