【作者】 穆洁； 陈瑞扬； 边学襄；

【Author】 Mu Jie Chen Ruiyang Bian Xuexiang Tianjin stomatlogoical hospital

【机构】 天津市口腔医院；

【摘要】 <正>目的:研究和探讨OKC癌变的临床与组织病理学特征。方法:对226例OKC临床病理资料进行研究分析,结果:226例OKC中,6例OKC发生癌变。癌变病例临床特征足:(1)患者年龄多在40岁以上。(2)病变局部反复感染史,病史一般超过3年。(3)X线影像为直径3～6．5cm多房透光区,边界较清,部分边界模糊。(4)术后多次复发。组织病理学特征是:(1)骨腔充满病变组织,类更多还原

【Abstract】 Objective: To study the clinical and histopathological features of the OKC with canceration. Methods: data of 226 cases with OKC were studied. PCNA monoclonal antibody were used to react on single and multiple cysts. Results: Out of 226 cases with OKC, 6 cases are companied with canceration. The clinical features of the cases with canceration are: (1)patients’s ages are older. (2)recurrent local infection history. (3)X-ray images show transparent areas which have diameter of 3～6.5cm. the image boundaries are clear but partial boundaries are not clear. Histopatholgical features are: (1)The bone cystic cavities are filled with lesion tissues, like solid tumor. (2)all cases with canceration are multiple cysts but single cysts. Multiple cystic structures filled with keratotic material. (3)The lining epithelial cells proliferate abnormally. Partial proliferating cells present a typical suqamous cell carcinoma structure. Local bone is destroyed and metastasis may occur. Expressions of PCNA lining epithelium of multiple cysts are stronger than that of single cysts. Conclusion: There are evident clinical and pathological features in OKC with canceration. The lining epithelium of multiple cysts have more peroliferati activity on single cysts and have canceration potentiality.更多还原