The expression and function research of Lon protein from Thermus thermophilus HB8

【作者】 刘晓晴；

【Author】 Wang Xin Liu Xiaoqing College of Life Science,Capital Normal University (Beijing,100037)

【机构】 College of Life Science,Capital Normal University；

【摘要】 <正>There are two different types of proteases,which are with respect to their ATP requirement for the proteolytic process; traditional proteases represented by trypsin do not require ATP for the hydrolysis of peptide bonds,whereas Lon,Clp, HsIVU and eukaryote 26S proteasome require ATP for protein breakdown.Lon protease is the first ATP-dependent protease purified from Escherichia coli,and forms an oligomer consisting of identical subunits distinct from other ATP-更多还原