Exploring the Protection Mechanism of HdeA by FCS

【作者】 吴思； 赵新生；

【Author】 Wu Si Zhao Xinsheng Beijing National Laboratory for Molecular Sciences,State Key Laboratory for Structural Chemistry of Unstable and Stable Species,and Department of Chemical Biology,College of Chemistry and Molecular Engineering,Peking University,Beijing,100871,China Zhang Meng Chang Zengyi College of Life Sciences,Peking University,Beijing,100871

【机构】 Beijing National Laboratory for Molecular Sciences,State Key Laboratory for Structural Chemistry of Unstable and Stable Species,and Department of Chemical Biology,College of Chemistry and Molecular Engineering,Peking University；

【摘要】 <正>HdeA is a single domain protein which exists in the periplasm of Escherichia coli,and is found to be a acid resistence chaperone for the survival of the strain at low pH.Our experiments are performed to probe different aggregation state of HdeA from neutral condition to extremely acidic environment by fluorescence correlation spectroscopy.We get更多还原