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手术切口感染的病原菌分布及耐药性探讨

Investigation into pathogen distribution and drug resistance in Infection of Operative Incision

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【作者】 谢明水晏文强熊建华

【Author】 XIE Mingshui YAN Wenqiang XIONG Jianhua(Laboratory Department,Central Hospital of Suizhou.Suizhou,Hubei,441300)

【机构】 随州市中心医院检验科

【摘要】 目的探讨手术切口感染病原菌的分布及耐药性,给临床防治手术切口感染提供科学依据。方法菌株分离鉴定按《全国临床检验操作规程》进行,药敏试验采用DADE BEHRING专用细菌鉴定药敏复合板。结果140株病原菌以革兰阴性杆菌(GNB)为主,检出82株,占58.6%。革兰阳性球菌58株,占41.4%.其中金黄色葡萄球菌(SA)和铜绿假单胞菌(PAE)检出率较高,分别为29.3%与27.1%.菌株均显示出较高的耐药性,其中耐甲氧西林金黄色葡萄球菌(MRSA)占Sep总数的31.7%(13/41);产超广谱β-内酰胺酶(ESBLs)大肠埃希菌和肺炎克雷伯菌检出率为40.9%(18/44).结论必须采取有效的防治措施,预防与控制手术切口感染。

【Abstract】 Objective To investigate pathogen distribution and drug resistance in infection of operative incision and provide the reference for clinical prevention and cure. Methods Referring to Rules of Operation in Clincal Laboratory of Nationwide,strains were isolated and identified,and drug-sensitivity test was performed by DADE BEHRING pannel. Results Among total 140 strains of pathogenic bacteria,the most were gram negative bacilli that accouted for 58.6%(82 strains),followed by gram positive coccus that accouted for 41.4%(58 strains).Staphylococcus aureus and pseudomonas aeruginosa had the higher detection rate.The former was 29.3%and the latter was 27.1%.Among the total Staphylococcus aureus,methicillin resistant staphylococcus aureus(MRSA)accouted for 31.7%(13/41),Detection rate of extended-spectrum beta-lactamase(ESBL)producing E.coli and pneumonia klebsiella was 40.9% (18/44).Conclusion Effective measurement should be taken to prevent and control infection of operative incision.

【关键词】 手术切口感染病原菌耐药性
【Key words】 Operative incisionInfectionPathogenic bacteriaDrug-resistance
  • 【会议录名称】 湖北省暨武汉市微生物学会分析微生物专业委员会第十届第五次学术会议论文汇编
  • 【会议名称】湖北省暨武汉市微生物学会分析微生物专业委员会第十届第五次学术会议
  • 【会议时间】2008-04
  • 【会议地点】中国湖北黄石
  • 【分类号】R446.5
  • 【主办单位】湖北省微生物学会分析微生物专业委员会、武汉市微生物学会分析微生物专业委员会
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