【作者】 刘国政； 谢明水； 晏文强； 熊建华；

【Author】 LIUGUOZHENG,XIE Mingshui,YAN Wenqiang,XIONG Jianhua(Laboratory Department,Central Hospital of Suizhou.Suizhou,Hubei,441300)

【机构】 随州市中心医院检验科；

【摘要】 目的了解我院重症监护病房(ICU)呼吸机相关性肺炎的病原菌及其耐药性,为临床防治提供依据。方法对ICU138例呼吸机相关性肺炎患者的发病年龄、基础疾病、病原菌构成及耐药率进行分析。结果共检出病原菌138株,其中革兰阴性菌(G~-)占69.6 %(96/138);革兰阳性菌(G~+)占20.3%(28/138);真菌占10.1%(14/138)。病原菌中铜绿假单胞菌分离率最高;产ESBLs细菌分离率为34.2%(13/38);甲氧西林耐药葡萄球菌(MRS)在葡萄球菌中分离率为32.1%(8/28);G~-杆菌的耐药检测结果显示呈多重耐药性。结论ICU呼吸机相关性肺炎病原体以G-菌为主,临床应重视病原体的检查,合理使用抗生素。更多还原

【Abstract】 OBJECTIVE To investigate the pathogen spectrum distribution and antimicrobial resistance in ventilator-associated pneumonia in ICU and provide the reference for clinical prevention and treatment.METHODS Among 138 patients with ventilator-associated pneumonia,the ages,underlying diseases,pathogens distribution and resistance rate were analyzed.RESULTS Among 138 strains of isolated pathogens,the gram-negative bacteria accounted for 69.6%(96/138),the gram-positive bacteria for 20.3%(28/138),and the fungi for 10.1%(14/138).The isolating rate of Pseudomonas aeruginosa was the most highest.The isolating rate of ESBLs producing strains was 34.2%(13/38).Among the total staphylococci, isolating rate of methicillin-resistant staphylococci(MRS)was 32.1%(8/28).Gram-negative bacilli showed multiple drug-resistance.CONCLUSIONS Gram-negative bacteria was the majority of the pathogens isolated from patients with ventilator-associated pneumonia in ICU.The clinical doctors should think highly of pathogen detection and rational application of antibiotics.更多还原