【作者】 申建维； 吴远志； 许平； 金伟杰； 程冬娥； 孙秀琴； 张鸿；

【Author】 SHEN jian-wei WU yuan-zhi XU-pin(Second Employees’Hospital of Wu Gang,Wuhan Hubei 430085,China)

【机构】 武钢第二职工医院检验科；

【摘要】 目的探讨我院肿瘤科病区医院感染的病原菌分布特点和耐药性,以制定干预对策。方法采取前瞻性监测与回顾性调查相结合的方法,对肿瘤科病区198例医院感染病例进行统计分析。结果我院肿瘤科病区医院感染部位以下呼吸道为主,占68.2%(135/198);第二位为泌尿道,占16.7%(33/198);感染病原菌主要有铜绿假单胞菌(20.2%)、肺炎克雷伯菌(19.2%)、大肠埃希菌(16.2%)、金黄色葡萄球菌(10.6%)等,以上病原菌均为多重耐药菌。其中,产超广谱β-内酰胺酶(ESBLs)肠杆菌科细菌检出率为45.7%(32/70),甲氧西林耐药葡萄球菌(MRS)检出率为40.6%(13/32)。结论肿瘤科医院感染病原菌的耐药性已十分严重,应采取综合性干预对策,降低医院感染率。更多还原

【Abstract】 OBJECTIVE to approach the pathogenic distribution of nosocomial infection and drug-resistance in tumor department to formulate the intervention strategy.METHOD Prospective monitoring and retrospective investigation were performed to analyze the 198 cases of nosocomial infection in tumor department.RESULT The lower respiratory tract infection was the main infection in tumor department,accounting for 68.2%(135/198).The urinary tract infection rated the second,accounting for 16.7%(33/198).Pathogenic bacteria mainly included Pseudomonas aeruginosa(20.2%),Klebsiella pneumoniae(19.2%),Escherichia coli(16.2%), Staphylococcus aureus(10.6%),and etc.Above pathogenic bacteria were all multidrug-resistant. Detection rate of extended spectrumβ-lactamase(ESBLs)producing Enterobacteriaceae strains were 45.7%(32/70).Detection rate of methicillin-resistant Staphylococci(MRS)was 40.6%(13/32).CONCLUSION Drug-resistance status of nosocomial infection was very serious in tumor department.Comprehensive intervention strategy should be adopt to decrease the infection rate.更多还原