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440种贵州中草药的体外抗真菌作用

Anti-Fungi Effect in vitro of 440 Traditional Chinese Medicinal Herbs Collected from Guizhou

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【作者】 陈阿英左丽杨燕

【Author】 CHEN A-ying~1, ZUO Li~(1, 2), YANG Yan~2(1. Department of Immunology, Guiyang Medical College, Guiyang 550004, Guizhou, China; 2. The Center of Tissue Engineering and Stem Cell Reaserch, Guiyang Medical College, Guiyang 550004, Guizhou, China)

【机构】 贵阳医学院免疫学教研室贵阳医学院免疫学教研贵阳医学院组织工程与干细胞实验中心

【摘要】 应用试管法研究了贵州440种中草药提取物对红色毛癣菌、石膏样小孢子菌生长繁殖的影响。研究表明440种中草药提取物中有29种(6.59%)对红色毛癣菌有抑制和杀菌作用,其最低抑菌浓度(MIC)与最低杀菌浓度(MBC)的范围为2.5%~20%;15种(占3.41%)对石膏样小孢子菌有抑菌和杀菌作用,其MIC和MBC的范围为2.5%~20%,其中11种中草药对两种真菌均有抑菌和杀菌作用。实验证实贵州中草药中有部分药物对红色毛癣菌、石膏样小孢子菌有较强的抑制和杀菌作用。

【Abstract】 The growth of T.rubrum and Microsporumgypseum were investigated with each extract of 440 medicinal herbs collected from Guizhou by serial dilution respectively. The results show that 6.59%(29/440) of these extracts could inhibit the growth of T.rubrurn or kill it; the range of MIC, MBC was 2.5%~20%. On the other hand, there were 15 extracts of 440 medicinal herbs(3.41%) that could inhibit the growth of Microsporurngypseum or kill it; the range of MIC, MBC was 2.5%~20%. Moreover, both of fungi were restrained and killed by 11 extracts of 440 medicinal herbs. Conclusionly, the assay indicated some certain traditional Chinese medicinal herbs collected from Guizhou have the capacity of anti-fungi through inhibiting the growth of T.rubrurn and Microsporumgypseum or killing it.

【基金】 贵州省专项重大课题资助项目(黔科合中药专字[2003]07)
  • 【会议录名称】 生命科学与微生物专辑
  • 【会议时间】2004
  • 【分类号】R285
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