【作者】 张王志； 全学军； 周大利； 尹光福；

【Author】 ZHANG Wang-zhi~1 QUAN Xue-jun~2 ZHOU Da-li~3 YIN Guang-fu~3 (1.College of Mathematics & Physics,Chongqing Institute of Technology,Chongqing 400050,China; 2.College of Bioengineering,Chongqing Institute of Technology,Chongqing 400050,China; 3.College of Material Science and Engineering,Sichuan University,Chengdu 610064,China)

【机构】 重庆工学院数理学院； 重庆工学院生物工程学院； 四川大学材料学院；

【摘要】 通过溶胶-凝胶(sol-gel)工艺制备了一种掺铕磷灰石/硅灰石磁性生物玻璃陶瓷(apatite-wollastonite magnetic glass ceramic,AW MGC)．采用 X 射线衍射 (XRD)、扫描电镜(SEM)、能谱(EDS)、振动磁强计(VSM)等方法分析材料晶相组成、显微结构、磁性、生物活性；并通过与人肝细胞 LO2、骨髓基质干细胞 (MSC)复合培养对新制备的 AW MGC 的生物相容性及其对人体细胞的作用进行了实验分析．结果表明：掺有适量稀土铕(Eu)的生物玻璃陶瓷既能够保持良好的生物活性,又能表现出一定的磁性．是一类十分具有发展潜力的骨修复材料、骨组织工程支架材料．更多还原

【Abstract】 A novel Europium doped magnetic bioactive glass-ceramic has been synthesized from sol-gel process. Characteristics of the materials were determined with X-ray diffraction (XRD),scan electron microscopy (SEM),energy dispersive spectrum (EDS),vibrating sample magnetometer (VSM) and so on.Experiment of culturing LO2 liver cells and rabbit marrow stromal cells with the material was carried to evaluate the biocompatibility and the ability to induce cell differentiation.Results show that:The novel europium doped magnetic bioactive glass-ceramic remain bioactivity while it shows magnetism.It’s a sort of excellent materials of bone repaired and hyperthermia.更多还原