【作者】 姜翠凤； 江万权； 郝凌云； 龚兴龙； 曹真； 顾瑞；

【Author】 JIANG Cui-feng~1 JIANG Wan-quan~1 HAO Ling-yun~(2,3) GONG Xing-long~2 CAO Zhen~1 GU Rui~2 (1.Department of Chemistry,University of Science and Technology of China,Hefei 230026,China; 2.Department of Mechanics and Mechanical Engieering,University of Science and Technology of China,CAS Key Laboratory of Mechanical Behavior and Design of Materials,Hefei 230027,China; 3.Fuyang Normal College,Fuyang 236032,China)

【机构】 中国科学技术大学化学系； 中国科学技术大学力学和机械工程系,中科院材料力学行为与设计重点实验室；

【摘要】 首先以单分散性良好的 PSA 为模板,用还原铁盐方法生成 PSA@Fe₃O₄核壳结构复合微球．再将生成的粒子加入到四氩呋喃（THF）溶剂中,使 PSA 模板溶解,得到 Fe₃O₄空心微球．在一定条件下将葡聚糖吸附在磁性微球表面,得到吸附有高分子的磁性微球．采用 X 射线衍射（XRD）、透射电子显微镜（TEM）、傅立叶变换红外光谱（FT-IR）和热重分析（TGA）对制备的微球进行表征．粒子大小均匀,平均直径在50nm 左右,Fe₃O₄层厚约为5nm．这种新颖的磁性高分子微球具有纳米级的尺寸和独特的空心结构．在生物医学领域特别是药物输运上可能具有广阔的应用前景．更多还原

【Abstract】 An improved method of preparing magnetite-dextran microsphere is proposed.Several parameters were evaluated and the characteristics of the microspheres were investigated by XRD,TEM,FT-IRand TGA.The XRD results showed that the particles were indeed Fe₃O₄.The transmission electron microscope images of the PSA@Fe₃O₄ exhibited that the nanoparticles with a diameter in the range of 30-100nm,the mean diameter is about 50nm.The resultant nanoparticles could be to have the capacity of encapsulation.更多还原