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硫酸钙多孔支架材料的制备及其结构和性能的研究

Study on the structure and characteristics of CaSO4 porous scaffold

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【作者】 游秀东高建平朱孟府张西正

【Author】 YOU Xiu-dong~(1,2) GAO Jian-ping~2 ZHU Meng-fu~1 ZHANG Xi-zheng~1 1.Institute of Medical Equipment,Academy of Military Medical Sciences,National Engineering Research Center for

【机构】 军事医学科学院卫生装备研究所国家生物防护装备工程技术研究中心天津大学理学院

【摘要】 以硫酸钙为基材,采用粒子沥出法构制出了 SCCS、GLCS 系列多孔支架材料,并对二者的结构及特性进行了研究.X 射线衍射分析结果表明二者晶体属同一晶系,但 SEM 结果表明晶体的形貌却不同,SCCS 系列晶体为多角形结构,而 GLCS 系列晶体为长针状结构,这样就造成二者在力学强度和降解速度上的差异.

【Abstract】 Calcium sulfate (CS),as a restore material,exists biocompatibility,biodegradability and osteoconduetivity.So the studies about using CS as repairing fillers for the treatment of bone defection are reported now and then.But the fabrication of CS porous scaffold has not been reported,so we use calcium sulfate as the basic material to fabricate CS porous scaffold as bone restore materials for tissue engineering,and study the structure and characteristics of the materials by X-ray diffraction and SEM. SCCS and GLCS series porous scaffolds are prepared by using particle-leaching technique.X-ray analysis indicates that the crystal patterns of the two sets of samples are similar,but SEM shows that the appearances of them are different.The CS crystals in SCCS series porous scaffolds are polygon,but that in the GLCS series porous scaffolds are needle shape.This leads to the differences in mechanical intensity and the absorption rates in vitro of these two series of CS scaffold.

【关键词】 硫酸钙多孔支架体外
【Key words】 calcium sulfateporous scaffoldin vitro
  • 【会议录名称】 第六届中国功能材料及其应用学术会议论文集(5)
  • 【会议名称】第六届中国功能材料及其应用学术会议
  • 【会议时间】2007-11
  • 【会议地点】中国湖北武汉
  • 【分类号】R318.08
  • 【主办单位】重庆仪器材料研究所、中国仪器仪表学会仪表材料分会、国家仪表功能材料工程技术研究中心
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