【作者】 陈蓉； 张绍祥； 尹志勇； 赵辉； 张伟国； 陈金华；

【Author】 CHEN Rong1, ZHANG Shaoxiang2*, YIN Zhiyong3, ZHAO Hui3, ZHANG Weiguo1, CHEN Jinhua1 (1.Department of Radiology, Institute of Surgery Research, Daping Hospital, Chongqing 400042, 2.Department of Anatomy, College of Medicine, Chongqing, 400038, 3.Chongqing Key Laboratory of Vehicle Crash/Bio-impact and traffic safety, Department 4th, Institute of Surgery Research, Daping Hospital, Third Military Medical University,Chongqing 400042,China)

【机构】 第三军医大学大坪医院野战外科研究所放射科； 第三军医大学基础部解剖教研室(重庆市计算医学研究所)； 大坪医院野战外科研究所四室车辆/生物碰撞安全重庆市市级重点实验室；

【摘要】 应用64层螺旋CT研究兔坠落式颅脑减速伤的伤情特点。实验用兔36只,包括对照组(6只)和致伤组(30只)。采用自行设计的减速伤致伤装置复制兔坠落式颅脑减速性损伤,致伤组根据不同致伤高度随机分为Ⅰ组(2.5m)、Ⅱ组(3.5m)和Ⅲ组(7m)。于致伤后3～4小时行64层螺旋CT扫描。观察兔颅脑减速伤的CT表现,并与大体解剖学观察结果、高速摄像系统所见进行对照。坠落高度越高,兔颅脑损伤越严重;蛛网膜下腔出血是最常见的颅内病灶;脑挫裂伤位于撞击处及对冲部位,以对冲部位更严重;颅底骨折均位于对冲部位。64层螺旋CT可准确显示颅骨骨折,且与高速摄像系统所记录的兔颅脑撞击部位一致。对兔颅脑损伤严重的Ⅲ组,64层螺旋CT基本上显示了所有颅脑损伤情况;Ⅱ组部分轻度损伤者CT扫描呈假阴性;Ⅰ组颅内CT表现均为真阴性。64层螺旋CT平扫可显示严重及部分轻-中度兔坠落式颅脑减速伤的伤情特点,能为其损伤机制的基础研究提供有价值的信息。更多还原

【Abstract】 To study the characteristic of deceleration brain injury from falls in rabbits by 64 multi-detectors CT. The deceleration brain injury was produced in rabbits by utilizing an impactor setup. The study included 36 rabbits (control group and experiment group), and the experiment group was divided randomly into 3 groups according to the fall height. Fall height of group Ⅰwas 2.5m, group Ⅱ3.5m, and group Ⅲ 7m. CT scanning was performed after 3～4 hours of trauma and CT features of deceleration brain injury of rabbits were compared with both macroscopic anatomy and high speed camera. The severity of brain injury of rabbits increased with fall height. Subarachnoid hemorrhage was the commonest intracranial lesion. Contusion and laceration of brain located at the site of impact and contra-coup (away from the site of impact), and the latter was more severe. Basal fracture located at the site of contra-coup. 64 multi-detectors CT display the shape and location of skull fracture exactly, and were corresponding with the site of impact recording by high speed camera. On CT scan, almost all of brain injuries were revealed in group Ⅲ, some minor brain injury of rabbits in group Ⅱwere false negative, and all rabbits were true negative in group Ⅰ. 64 multi-detectors CT could display the characteristic of deceleration brain injury from falls in rabbits. Data obtained by this procedure may provide valuable information for brain injury mechanism study.更多还原