【作者】 王艳； 田秀兰； 刘瑛林； 赵鸿； 王贵强； 于岩岩； 田庚善；

【Author】 the first hospital of Peking University Infectious disease department Wangyan Zhaohong Tian Xiulan Liu Yinglin Yu Yanyan Wang Guiqiang

【机构】 北京大学第一医院感染疾病科；

【摘要】 目的:研究肾血流动力学与肝病病程的关系,证实肾血流阻力指数可作为帮助诊断失代偿肝硬化病程的方法。从而,协助早期诊断肝肾综合征。方法:选择确诊失代偿肝硬化患者共41例,检测血肌酐、血胆红素、INR。并做多普勒超声检测肾血流阻力指数,用 SPSS12.0进行统计学处理,作相关性分析。结果:41例患者中平均年龄57岁,5例病因为 PBC,余36例均为 HBV 或 HCV 感染所致。MELD 积分分布:0-9分:8 例;10-19分:28例;19-29分:5例;≥30分:0例。MELD 积分与肾血流阻力指数的相关系数 r 值为0.502。证实 MELD 积分与肾血流阻力指数呈正相关。结论:彩色多普勒超声检测肾血血流阻力指数可以对病程的进展及疗效的评价有较大临床价值。由于操作简单,重复性好,无创伤性,可以比较准确地测定肝硬化的肾血流动力学的变化,因此,临床可帮助诊断失代偿肝硬化患者的病程及预后,并协助早期诊断肝肾综合征。更多还原

【Abstract】 Objective:To observe the renal hemodynamic changes in the patients with decompensated cirrhosis and study the relationship between the renal hemodynamic changes and MELD score.To provide a useful information in assessing prognosis.Methods:Hemodynamics of renal arcuate artery in 41 patients with decompensated cirrhosis were investigated.Test the serum creatinine,serum total bilirubin,INR and arcuate artery blood flow resistance index.The relationship of arcuate artery blood flow resistance index and MELD score was analyzed by SPSS12.0 software.Results:The relationship of renal hemodynamics and MELD score showed direct correlation.The coefficient correlation was 0.502.Conclusion:The renal hemodynamics changes of arcuate artery blood flow resistance index tested by color Doppler ultrasonography have a definite clinical value in assessing progress and prognosis in the patients with decompensated cirrhosis,and helping diagnosed HRS earlier.更多还原