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血液净化治疗重型肝炎中不良反应分析与探讨
Analysis and discuss the adverse affections in fulminate hepatitis patients during bioartfficial liver support system therapy
【作者】 李海; 唐克诚; 李谦; 卢诚震; 韩桂兰; 刘国旺; 袁桂玉; 朱理珉;
【Author】 Li Hal Tang Ke-cheng Li Qian Lu Cheng-zhen Han Gui-lan Liu Guo-wang Yuan Gui-yu Zhu Li—min
【机构】 天津市传染病医院;
【摘要】 目的:分析和探讨重型肝炎患者在血液净化过程中出现的不良反应,方法:对我院68名重型肝炎患者进行血浆置换和血液滤过治疗,观察治疗期间的不良反应。结果:血浆置换治疗时不良反应发生率为95.59%,常见为轻度不良反应(88.24%),严重不良反应发生率为7.5%,与患者治疗前病情有关,血液滤过治疗时不良反应发生率为22.58%,没有严重不良反应。结论:血浆置换比血液滤过的不良反应发生率高,严重不良反应与患者治疗前病情过重有关。
【Abstract】 OBJECTIVES:Analysis and discuss the adverse affections in fulminate hepatitis patients during bioartificial liver support system therapy.METHODS:Plasma exchange(PE)and plasma perfusion had been used to therapy 68 fulminate hepatitis admitted-patients,and adverse effects were observed during the therapy. RESULTS:The rate of adverse events during plasma exchange therapy is 95.59%,non-severe adverse effects are normal.The rate of severe adverse effects is 7.5 % and has the relationship with patient’ illness state before the therapy.The rate of adverse effects during plasma peffusion therapy is 22.58%,and no severe adverse effects were observed.CONCLUSIONS:The rate of adverse effects during plasma exchange therapy is higher than in plasma perfusion.The severe adverse effects have the relationship with patient’illness state before the therapy.
【Key words】 Bioartificial liver support system; adverse affections; Fulminate hepatitis;
- 【会议录名称】 第二届全国人工肝及血液净化学术年会论文集
- 【会议名称】第二届全国人工肝及血液净化学术年会
- 【会议时间】2005-09
- 【会议地点】中国辽宁大连
- 【分类号】R459.5;R575.1
- 【主办单位】全国重型肝病及人工肝血液净化攻关协作组、中国肝炎防治基金会人工肝及血液净化科技攻关基金委员会、中华医学会肝病学分会重型肝病与人工肝学组