【作者】 盖洪鹏； 纪民； 王汝刚； 孙勇；

【Author】 Gai hong-peng Ji min Wang ru-gang Sun yong.The No.6 hospital of Dalian.116001.

【机构】 大连市第六人民医院；

【摘要】 目的:通过对人工肝(ALSS)治疗重型肝炎疗效进行回顾性分析,探讨终末期肝病模型(MELD)在人工肝治疗重型肝炎效果的预期分析的临床应用价值。方法:分析我院276例已进行人工肝治疗的重型肝炎患者的治疗效果,对人工肝治疗前的 MELD 评分与治疗效果进行相关性的分析;并结合 CTP 分级进行对比分析。结果:除 MELD 评分≥40分的预期病死率和实际病死率相同外,其余各组均显示人工肝治疗重肝可降低3个月预期病死率;MELD 评分越高,病死率越高,而其中的 CTP-C 级的治疗效果越差。结论:人工肝治疗重型肝炎有肯定疗效,MELD 评价系统对判断人工肝治疗重型肝炎效果有预测作用;同时结合 CTP 分级在临床上有实际指导价值。更多还原

【Abstract】 Objective By the retrospective analysis of severe hepatitis treatment through artificial liver support system(ALSS),to argue the clinic value of the expectative analysis in which MELD in artificial liver support system.Methods analysis the treatment effect of 276 patients who are diagnosed as severe hepatitis throughout ALSS treatment,analysis the treat effect between the MELD score and the treatment effect,and the relationship between them with the Child-Turcotte-pugh(CTP)classification.Results except the common between the predicting mortality and the death rates in MELD(?)40 group,the other groups all indicate the decrease of 3-month predicting mortality in ALSS treatment.The more of MELD score,the higher in the 3-month predicting mortality,and in the high MELD score group,the treatment effect of CTP-C is worse.Conclusions the way of ALSS treatment in severe hepatitis is considered the sure effect.MDLE scale system is a system which can predict the effect in which through ALSS treat severe hepatitis,meanwhile combined with the CTP classification is instructive effect in clinical treatment.更多还原