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银杏叶制剂合并西酞普兰治疗血管性抑郁的对照研究
Contrast study of folium ginkgo preparation and citalopram combined treatment in vascular depression
【Author】 Chen Binhua,Qi Ruobing,Su Xueqian,Xia yong,Zhao Lijun.The Seventh Peoples Hospital of Hangzhou,Hangzhou 310013,china
【机构】 杭州市第七人民医院;
【摘要】 目的:探讨银杏叶制剂合并西酞普兰治疗血管性抑郁的疗效。方法:将62例血管性抑郁病人随机分为银杏叶制剂合并西酞普兰组(研究组)32例和单用西酞普兰(对照组)30例。在治疗前和治疗后4周、8周、12周分别用Hamilton抑郁量表(HAMD)评分,根据Hamilton抑郁量表平均分和总有效率评定疗效。结果:治疗8周后研究组HAMD评分低于对照组(P<0.05),治疗12周后研究组HAMD评分明显低于对照组(P<0.01)。治疗12周后研究组总有效率高于对照组(P<0.05)。结论:银杏叶制剂合并西酞普兰治疗血管性抑郁的疗效优于单用西酞普兰。
【Abstract】 Objective To investigate the efficacy of folium ginkgo preparation and citalopram combined treatment in vascular depression.Methods Patients with vascular depression (n=62) participated in our treatment study were randomly divided into folium ginkgo preparation in combination with citalopram group(investigation group,n=32) and citalopram single group(contrast group,n=30),change in depression mood was measured by the Hamilton depression scale(HAMD),before 4 weeks,8 weeks and 12 weeks after treatment,the effect were evaluated according to the average point of the Hamilton depression scale(HAMD) and the over effective rate.Results The HAMD score of the investigation group was lower than the contrast group 8 weeks after treatment(P<0.05),the HAMD score of the investigation group was lower remarkably than the contrast group 12 weeks after treatment(P<0.01),the over effective rate of the investigation group was higher than the contrast group 12 weeks after treatment(P<0.05). Conclusion The efficacy of folium ginkgo preparation and citalopram combined treatment in vascular depression is better than citalopram single.
【Key words】 vascular depression; therapy; folium ginkgo preparation; citalopram;
- 【会议录名称】 2009年浙江省医学会精神病学分会老年精神障碍学组学术会议论文汇编
- 【会议名称】2009年浙江省医学会精神病学分会老年精神障碍学组学术会议
- 【会议时间】2009-06-12
- 【会议地点】中国浙江湖州
- 【分类号】R749.13
- 【主办单位】浙江省医学会精神病学分会老年精神障碍学组