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Mechanisms of transcriptional regulation of POLH gene in response to the chemical carcinogen MNNG in cultured human amnion FL cells

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【作者】 朱慧芳范焰锋邵吉民

【Author】 Huifang Zhu,Yanfeng Fan,Jimin Shao~* Department of Pathology and Pathophysiology,Zhejiang University School of Medicine

【机构】 Department of Pathology and Pathophysiology,Zhejiang University School of Medicine

【摘要】 <正>DNA polymeraseηis a well-characterized Y-family DNA polymerase for translesion synthesis.We found that the expression of POLH gene was up-regulated in response to the alkylating agent N-methyl-N’-nitro-N-nitrosoguanidine(MNNG) in cultured human amnion FL

【基金】 supposed by grants from the National Natural Science Foundation of China (30770831);Zhejiang Provincial Natural Science Foundation for Excellent Research Groups (R207153).
  • 【会议录名称】 浙江省生理科学会2008年学术年会论文汇编
  • 【会议名称】浙江省生理科学会2008年学术年会
  • 【会议时间】2008-11-01
  • 【会议地点】中国浙江丽水
  • 【分类号】R114
  • 【主办单位】浙江省生理科学会
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