节点文献
Mechanisms of transcriptional regulation of POLH gene in response to the chemical carcinogen MNNG in cultured human amnion FL cells
【Author】 Huifang Zhu,Yanfeng Fan,Jimin Shao~* Department of Pathology and Pathophysiology,Zhejiang University School of Medicine
【机构】 Department of Pathology and Pathophysiology,Zhejiang University School of Medicine;
【摘要】 <正>DNA polymeraseηis a well-characterized Y-family DNA polymerase for translesion synthesis.We found that the expression of POLH gene was up-regulated in response to the alkylating agent N-methyl-N’-nitro-N-nitrosoguanidine(MNNG) in cultured human amnion FL
【Key words】 DNA polymeraseη;
chemical carcinogen;
N-methyl-N’-nitro-N-nitrosoguanidine(MNNG);
Gene expression,Transcription regulation;
【基金】 supposed by grants from the National Natural Science Foundation of China (30770831);Zhejiang Provincial Natural Science Foundation for Excellent Research Groups (R207153).
- 【会议录名称】 浙江省生理科学会2008年学术年会论文汇编
- 【会议名称】浙江省生理科学会2008年学术年会
- 【会议时间】2008-11-01
- 【会议地点】中国浙江丽水
- 【分类号】R114
- 【主办单位】浙江省生理科学会