【作者】 袁斌； 王爱华； 徐建亚； 朱越； 李琳；

【Author】 YUAN Bin~1 WANG Ai-hua~2 XUJian-ya~2 ZHUYue~2 LI Lin~2 (1 The Pediatric Department of The Affiliated Hospital of Nanjing University of TCM,Nanjing 210029;2Jiangsu Nanjing University of TCM,Nanjing 210029,Jiangsu)

【机构】 南京中医药大学附属医院； 南京中医药大学；

【摘要】 目的探讨清肺口服液对呼吸道合胞病毒肺炎患儿血清白介素-8(IL-8)、细胞间粘附分子-1(ICAM-1)的影响。方法采用酶联免疫吸附法(ELISA),测量8例RSV肺炎患儿治疗前后血清中IL-8、ICAM-1水平。结果清肺口服液治疗后患儿血清中IL-8水平比治疗前显著下降,而血清中ICAM-1水平比治疗前显著升高,差异有统计学意义(P<0.05)。结论清肺口服液可显著降低RSV肺炎患儿血清中IL-8水平,升高ICAM-1水平,可能与清肺口服液的免疫调节作用有关。更多还原

【Abstract】 Objective:To study the influence of Qingfei Oral Liquid on Serum Interleukin-8(IL-8) and Intercellular adhesion molecule-1(ICAM-1) in children with Respiratory Syncytial Viral Pneumonia.Method: Enzyme- linked immuno-sorbent assay was used to measure the levels of serum IL-8 and ICAM-1 in 8 children with Respiratory Syncytial Viral Pneumonia before and after the treatment with Qingfei Oral Liquid.Results:The level of serum IL-8 was obviously decreased,while the level of serum ICAM-1 was obviously increased compared with those before the treatment with Qingfei Oral Liquid,and the the difference had a statistical significance(P<0.05).Conclusion:Qingfei Oral Liquid can make the level of serum IL-8 lower and that of ICAM-1 higher in 8 children with Respiratory Syncytial Viral Pneumonia.更多还原