Impact of enterovirus 71 infection on the expression and role of carnitine palmitoyltransferase Ⅱ in mice brain and brain stem

【作者】 李继安； 韩振靓； 李菲； 陈宗波；

【机构】 青岛大学医学院附属医院；

【摘要】 <正>Background The carnitine palmitoyltransferase(CPT)system has crucial roles in the B-oxidation of longchain fatty acids,and is a pivotal component of ATP generation through mitochondrial fatty acid oxidation.The rate-limiting step in the importation of long-chain fatty acids into the mitochondria is the transesterification of acyl-coenzyme A(CoA)to acylcarnitine by CPTⅠ,while CPTⅡchanges the imported acylcarnitine back to acyl-更多还原