IVF-ET后异位妊娠相关因素探讨

【作者】 黄志辉； 余敏； 伍琼芳； 辛才林； 赵琰；

【机构】 江西省妇幼保健院辅助生殖中心；

【摘要】 目的探讨体外受精-胚胎移植(IVF-ET)后异位妊娠的相关因素。方法对我中心2006.09-2008.12与2009.1-2012.6所有接受IVF-ET获得临床妊娠的患者的临床资料进行回顾性研究,比较分析IVF-ET后异位妊娠相关因素。结果 2009.1-2012.6接受IVF-ET后异位妊娠率(2.69%)较2006.09-2008.12的异位妊娠率(7.84%)有显著性降低(P<0.001);改良移植推注方法 (OR=0.428,P<0.001)、HCG时子宫内膜厚度≥8mm(OR=0.521,P<0.001)是降低IVF-ET后异位妊娠的独立保护因素。结论在一定程度上改进移植推注方法和增加HCG日子宫内膜厚度可以明显降低IVF-ET后异位妊娠率。更多还原

【Abstract】 Objective To explore the related factors of ectopic pregnancy after in vitro fertilization and embryo transfer (IVF - ET).Methods Retrospectivily compare the cases of clinical pregnancy after IVF - ET treatment between 2006,Sep.and 2008,Dec.with the cases of clinical pregnancy after IVF - ET treatment between 2009, Jan.and 2012,Jun.in CenterofReproductive Medicine,Jiangxi Maternal & Child Health Care Hospital.Analyse the related factors of ectopic pregnancy after IVF - ET.Results Compared with the ectopic pregnancy rate (7.84%) between 2006,Sep.and 2008,Dec.,the ectopic pregnancy rate between 2009,Jan.and 2012, Jun.was significantly decreased(P <0.001 ).The ectopic pregnancy rate was significantly decreased in those patients with Improved transplantation push method(OR = 0.428,P < 0.001) and endometrial thickness≥8 mm(OR =0.521,P<0.001).Conclusions To a certain extent,improving transplantation push technique and increasing endometrial thickness on hCG day can obviously decrease ectopic pregnancy rate after IVF-ET.更多还原