Linkage Analysis of a large Chinese MHA pedigree in Hainan

【作者】 张淑芳；

【Author】 Zhang Shufang Xiangya HaiKou Hospital of Central South University,HaiKou,hainan,570208,China.

【机构】 Xiangya HaiKou Hospital of Central South University；

【摘要】 <正>Introduction May-Heggin anomaly is a well studied Mendelian disorder exhibiting an autosomal dominant inheritance pattern.The disease locus was first mapped to 22q12 by three independent groups at the turn of this century(Kunishima et al.1999,Kelley et al. 2000a,and Martignetti 2000).The initial availability of human genome sequence at that time facilitated the更多还原