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The Application of Oligonucleotide and Protein Double Recognition in the Detection of DNA Methylation with Surface Plasmon Resonance Biosensors

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【作者】 潘世扬徐建王芳束永前黄蕾

【机构】 南京医科大学第一附属医院

【摘要】 <正>Objective DNA methylation plays an essential role in maintaining cellular function.A growing number of human diseases have been found to be associated with aberrant DNA methylation,especially cancers.However,current technologies used in DNA methylation detection are complicated and time consuming.Surface plasmon resonance(SPR) biosensor technology is high sensitive for label-free analysis of biomolecular interactions.So we tried to establish a simple, rapid and specific technique based on SPR biosensors to detect DNA methylation.

  • 【会议录名称】 中华医学会第八次全国检验医学学术会议暨中华医学会检验分会成立30周年庆典大会资料汇编
  • 【会议名称】中华医学会第八次全国检验医学学术会议暨中华医学会检验分会成立30周年庆典大会
  • 【会议时间】2009-11-05
  • 【会议地点】中国北京
  • 【分类号】R450
  • 【主办单位】中华医学会(Chinese Medical Association)、中华医学会检验分会(Chinese Society of Laboratory Medicine)
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