【作者】 符文彬； 梁兆晖； 徐书君； 张继福； 何泽慧； 欧爱华；

【Author】 FU Wen-Bin~1,LIANG Zhao-Hui,XU Shu-jun~5,ZHANG Ji-Fu~1,HE Ze-hui~4,OU Ai-Hua~4 1 Department of Acupuncture and Moxibustion,Guangdong Provincial Hospital of Chinese Medicine,Guangzhou,510120 2 Research Team of Acupuncture Effect and Mechanism,Guangdong Provincial Academy of Chinese Medical Sciences, Guangzhou,510120 3 School of Acupuncture and Moxibustion,Guangzhou University of Chinese Medicine,Guangzhou,510405 4 Department of Applied Clinical Epidemiology,Guangdong Provincial Hospital of Chinese Medicine,Guangzhou,510120

【机构】 广东省中医院针灸科； 广东省中医药科学院针灸效应规律及机制研究团队； 广州中医药大学针灸推拿学院； 广东省中医院临床流行病应用研究室；

【摘要】 目的:评价NPQ颈痛量表作为疗效评价指标对中国慢性颈痛患者的适用性。方法:以麦吉尔疼痛量表(MPQ)和SF-36生存质量量表为参照,对一项多中心随机对照临床试验中896例患者治疗前后和随访中的所测量的NPQ评分进行信度、效度、反应度评价。其中以克朗巴赫α系数作为信度评价指标,以不同量表和NPQ颈痛量表内部各条目之间的Spearman相关系数作为效度评价指标,以不同评价时点的NPQ评分作为反应度的评价指标。结果:反映NPQ量表信度的克朗巴赫α系数为0.769(95%CI:0.761～0.804),除去驾驶条目的克朗巴赫α系数为0.783(95%CI:0.761～0.804)。效度分析提示,NPQ评分与MPQ量表各个领域是一般到中等强度的相关,与SF-36量表中的躯体疼痛领域为中到强相关,与其他六个领域为一般相关,与精神健康为弱相关。反应度分析提示,患者在治疗结束时和随访三个月后的NPQ评分与治疗前的NPQ评分差异均有统计学意义(P<0.001)。结论:NPQ颈痛量表具有良好的信度、效度和反应度,能够准确测量颈椎病颈痛患者的病情和功能状况,能够在评价针刺治疗颈椎病颈痛的临床试验中作为可靠的疗效指标。更多还原

【Abstract】 Objective to evaluate the reliability and validity of NPQ neck pain questionnaire as efficacy outcome for patients with chronic neck pain in China.Method the NPQ measures of 896 patients from a multi-center randomized controlled trial,including the outcomes before, after and during the follow-up survey were used to assess the reliability,validity,responsiveness of NPQ with McGill Pain Questionnaire(MPQ) and SF-36 QoL questionnaire as references. Cronbach’s a was used as the indicator of reliability;Spearman correlation coefficient between the questionnaires and among different items of NPQ was used as the indicator of validity;and the NPQ outcomes in different measuring time was used as indicator of responsiveness.Result the Cronbach’s a of NPQ was 0.769(95%CI:0.761～0.804),and 0.783(95%CI:0.761～0.804) when excluding the driving item.In the analysis of validity,NPQ was moderately correlated to the domains of MPQ,was moderately to strongly correlated to the body pain domain,weakly correlated to the mental health domain and moderately correlated to the rest 6 domains.For responsiveness,the NPQ outcomes after treatment and during the follow-up were statistically different from those before the treatment(P<0.001).Conclusion the NPQ questionnaire has good reliability,validity and responsiveness,which is capable to accurately measure the pain seriousness and function of patients with neck pain caused by cervical spondylosis,Therefore,it is a reliable indicator for efficacy evaluation in clinical trials of acupuncture.更多还原