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气导短纯音诱发的眼肌前庭诱发肌源性电位在健康青年人群中的波形特征

Characteristics of the air-conducted ocular evoked myogenic potential in the young normal Chinese subjects

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【作者】 张青宋辉胡娟陈彦飞张滟杜小滢张全安韦俊荣许珉加我君孝

【Author】 ZHANG Qing~*,SONG Hui,HU Juan,CHEN Yan-fei,ZHANG Yan,DU Xiao-ying,ZHANG Quan-an,WEI Jun-rong,XU Min,KAGA Kimitaka.*Department of Otorhinolaryngology Head and Neck Surgery,Second Affiliated Hospital,Xi’an Jiaotong University College of Medicine,Ear Institute of Xi’an Jiaotong University College of Medicine,Xi’an 710004,China

【机构】 西安交通大学医学院第二附属医院耳鼻咽喉 头颈外科病院西安交通大学医学院耳病研究所日本东京医疗中心 日本国立感觉器官研究所

【摘要】 目的介绍气导短纯音诱发的眼肌前庭诱发肌源性电位(ocular vestibular evokedmyogenic potential,oVEMP)的引出方法;观察健康青年人群oVEMP反应,并进行参数分析和正常值计算。方法选择25名健康成人作为研究对象,其中男12名,女13名,年龄19~45岁,平均年龄(24.3±5.6)岁。以500 Hz短纯音为刺激音,进行气导oVEMP检测,并计算阈值、潜伏期等参数的正常值。结果全部受试者均引出典型的oVEMP N1-P1复合波形,引出率为100%。oVEMP的引出阈值(正常听力级)为(86.6±3.6)dB(x±s,下同);N1潜伏期为(10.1±0.4)ms,P1潜伏期为(14.7±1.2)ms,波间期(4.5±1.0)ms;振幅(7.9±4.4)μV。除振幅耳间波动稍大外,oVEMP阈值、N1潜伏期及P1潜伏期左右耳间波动很小。结论气导oVEMP是一种新兴的、稳定有效的前庭功能检测方法。

【Abstract】 Objective To identify the characteristics of the air-conducted ocular vestibular-evoked myogenic potential(oVEMP) in the young normal Chinese subjects.Methods Twenty five normal subjects were recruited for conventional examinations of oVEMP.The subjects were 19-45 years of age[(24.3±5.6)years],12 males and 13 females.500 Hz air-conducted tone burst was employed for examination.The threshold of oYEMP in each ear was examined;patterns of these waves were observed and the nonnal ranges of the oVEMP waves responded to 100 dBnHL were calculated.Results All subjects were elicited with normal oVEMP N1-P1 waves in both ears.The response rate in these subjects was 100%.The threshold of oVEMP examination was(86.6±3.6) dBnHL(x±s),latency N1(101±0.4)ms,latency P1(14.7±1.2)ms,interval N1-P1(4.5±1.0) ms,amplitude(7.9±4.4)μV.Conclusions Air-conducted oVEMP is a kind of vestibular-ocular reflex respond to intensive sound generated by otolithic vestibular end organs.It is stable in the young normal subjects with minor variabilities.

【基金】 科技部“十一五”科技支撑计划项目(2007BAI18B13);国家自然科学基金(3073300/C170703);西安交通大学医学院第二附属医院2011年新技术新疗法基金(2011015);西安交通大学校长基金(xjj2008019)
  • 【会议录名称】 中国中西医结合学会耳鼻咽喉科专业委员会第十三次学术会议、浙江省中西医结合学会耳鼻咽喉科专业委员会第十一次学术会议论文汇编
  • 【会议名称】中国中西医结合学会耳鼻咽喉科专业委员会第十三次学术会议、浙江省中西医结合学会耳鼻咽喉科专业委员会第十一次学术会议
  • 【会议时间】2013-05-24
  • 【会议地点】中国浙江嘉兴
  • 【分类号】R764
  • 【主办单位】中国中西医结合学会耳鼻咽喉科专业委员会、浙江省中西医结合学会耳鼻咽喉科专业委员会
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