Long-term artificial selection reveals a role of TCTP in autophagy in mammalian cells

【作者】 Ke Chen； Chunhua Huang； Jia Yuan； Hanhua Cheng； 周荣家；

【Author】 Ke Chen;Chunhua Huang;Jia Yuan;Hanhua Cheng;Rongjia Zhou;Department of Genetics,College of Life Sciences,Wuhan University;

【机构】 Department of Genetics,College of Life Sciences,Wuhan University；

【摘要】 <正>Understanding genomic variation and detecting selection signatures in a genome under selection have been great challenges for a century.In mammalian ovary,activation,development/exhaustion of primordial follicles determines reproductive success,menopause/end of female reproductive life.However,molecular mechanisms underlying oogenesis,particularly under artificial selection,are largely unknown.We report that a proteome-wide scan for selection signatures更多还原