Prediction of genes related to obesity using eQTL information

【作者】 陶元娟； 孙啸； 谢建明；

【Author】 Yuanjuan.Tao,Xiao.Sun~* Jianming.Xie State Key Laboratory of Bioelectronics,School of Biological Science and Medical Engineering, Southeast University,Nanjing 210096,China

【机构】 东南大学生命科学与医学工程学院生物电子学国家重点实验室；

【摘要】 <正>Introduction Mining complex human disease genes is very important to understand disease pathogenesis and improve clinical treatment.It’s difficult to identify genes underlying complex disease because they are generally controlled by multiple genes and environment.Traditional experimental methods have discovered a large number of candidate genes,but it’s still a challenge.Nowadays,bioinformatics and computational biology are applied to facilitate the research due to the accumulation of huge amount of genomic data.更多还原