Binding-Peptide Prediction of HLA-1 on Unknown Alleles by Integrating Sequence Information and Energies of Contact Residues

【作者】 罗飞； 曾涛； 高洋洋； 刘娟；

【Author】 Fei Luo,Tao Zeng,Yangyang Gao and Juan Liu School of Computer,Wuhan University Wuhan,Hubei,430072,China

【机构】 武汉大学计算机学院；

【摘要】 <正>Motivation: In the cellular immune system,binding of peptides to Major Histocompatibility Complex (MHC) is the single most selective step in recognition of pathogens.Recently,a large number of prediction models and methods have been proposed to identify which peptides could bind to the given MHC molecule.Some state-of-the-art methods are reported to be更多还原