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板蓝根多糖对缺乳仔鼠小肠IgG和SIgA阳性细胞发育的影响

Effect of RIP on the expression of IgG and SIgA positive cells in the lacking milk renewal rats

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【作者】 黄鹏张婷婷张学武陶孟杰张书松

【Author】 HUANG Peng,ZHANG Tingt-ting,ZHANG Xue-wu,Tao Meng-jie,XIAO Chuan-bin~* (College of Animal Science and Veterinary Medicine,Henan Agricultural University, Zhengzhou 450002,China)

【机构】 河南农业大学牧医工程学院

【摘要】 应用免疫组化方法检测缺乳仔鼠小肠内分泌型免疫球蛋白阳性反应物的数量及分布变化来研究添加不同剂量板蓝根多糖(RIP)对缺乳仔鼠肠道黏膜免疫细胞的影响。结果表明,RIP可以促进缺乳仔鼠肠道黏膜IgG、SIgA阳性淋巴细胞的分泌,RIP对各肠段黏膜IgG、SIgA阳性淋巴细胞数量影响效果最明显的剂量随日龄增加而减小。结论:RIP能够提高小肠黏膜IgG、SIgA阳性细胞的水平量,增强肠道黏膜表面的抵御能力,提高机体免疫力。

【Abstract】 Using the immunohistochemistry to detect the intestine IgA plasma cells and the positive changes in number and distribution of objects in the lacking milk renewal rats to study the effect of lacking milk renewal rats intestinal mucosal immune cells of adding different doses RIP.Results were as follows:RIP could increase the contents of IgA and IgG in peripheral blood of the lacking milk renewal rats,and the best doses of RIP were decreased by the days.This study indicated that certain dose RIP could significantly improve the intestinal IgG and SIgA-positive material per unit area volume,and enhance the resilience of the surface of intestinal mucosa,and improve immunity.

【关键词】 RIP缺乳仔鼠小肠SIgAIgG
【Key words】 RIPlacking milk renewal ratssmall intestineSIgAIgG
  • 【会议录名称】 中国畜牧兽医学会动物解剖学及组织胚胎学分会第十七次学术研讨会论文集(上)
  • 【会议名称】中国畜牧兽医学会动物解剖学及组织胚胎学分会第十七次学术研讨会
  • 【会议时间】2012-07-10
  • 【会议地点】中国山西太谷
  • 【分类号】S853.7
  • 【主办单位】中国畜牧兽医学会动物解剖学及组织胚胎学分会
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