【作者】 李生杰； 颜永年； 王小红； 张婷； 张人佶； 林峰；

【Author】 Li Shengjie,Yan Yongnian,Wang Xiaohong,Zhang Ting,Zhang Renji,Lin Feng

【机构】 清华大学机械工程系/先进成形制造教育部重点实验室；

【摘要】 基于多喷头的细胞受控组装技术,是快速成形技术与组织工程的交叉创新,是制备人体损伤组织器官替代物的重要途径。喷头的启停响应是其中的关键技术之一,与挤出单元的弹性形变密切相关。构建多喷头细胞组装试验系统,并对挤出过程进行了分析和试验验证。采用分段温度控制减小挤压力和弹性形变,并通过在启停过程中进行弹性形变的补偿-释放控制,有效地减小了启停挤出过程的响应延迟和流涎量,保证了多种细胞的受控组装成形精度。更多还原

【Abstract】 Multi-nozzle cell assembling technology,an innovative interdiscipline based on rapid prototyping and tissue engineering,is an important method to develop substitutes for injured human tissue /organs.Its key restricting problem is the nozzle-opening /closing response,which is related with the elastic deformation of the extrusion unit in extruding process.An experiment system is set up and the analysis and experimental verification is presented.After adopting the sub-section temperature-controlling method in extruding process to reduce the extrusion force and the elastic deformation, and compensating /releasing the elastic deformation in nozzle-opening /closing process,the response delay /salivation phenomenon have been greatly restrained and multi-cell controlled assembling process has been accomplished with good accuracy.更多还原